In business since 2002, we have been filling prescriptions for some of the most popular breeders in the country. Join your colleagues in using BET Pharmacy to meet your compounding needs. At BET Pharmacy all of our employees are also involved in the equine industry outside of BET. We truly have a passion for horses and it shows when you give us a call, which is why we’ve had such great feedback from our clients.
BET PHARM maintains strict quality control. All injectables undergo rigorous sterility testing. We adhere to external quality control monitoring by independent labs, such as Analytical Research Laboratories for stability, pyrogens, purity and verification of prescribed potency as well as our adherence to standards set forth in the USP 797 guidelines. Our quality assurance program is designed to ensure every prescription meets your specifications. Our pharmacists have extensive training in compounding procedures and utilize a class 100/ ISO 5 cleanroom to prepare our compounds in our state-licensed facility. When you choose BET Pharmacy you can be confident your patients will receive medications of the highest quality.
Cushing’s disease in dogs: Cabergoline treatment
V.A. Castillo *, N.V. Go´mez, J.C. Lalia, M.F. Cabrera Blatter, J.D. Garcı´a
Rebekah C. Hebert MS, Donald L. Thompson Jr. PhD, Pamela B. Mitcham PhD, Jeanne D. Lestelle MS, Richard M. Gilley BS (BioRelease Technologies), Patrick J. Burns PhD (BioRelease Technologies)
Long term treatment of insulin insensitive mares with cabergoline long term treatment jevs 2014
N. Arana Valencia, D.L. Thompson, E.L. Oberhaus, R.M. Gilley
Comparison of Efficacy of Two Dose Rates of Histrelin to Human Chorionic Gonadotropin for Inducing Ovulation in Broodmares
Justin L Voge DVM, MS, Diplomate ACT, A. Kendrick Sudderth DVM, Steve P. Brinsko DVM, MS, PhD, Dipolmate ACT, Patrick J. Burns PhD, Terry L. Blanchard DVM, MS, Diplomate ACT
Abstract – Ovulation induction for embryo transfer: hCG versus GnRH analogue
Michaela Kolling and W.R. Allen
Clinical Comparison of 3 products available to hasten ovulation in cyclic mares C. J. Berezowski, DVM, K. L. Stitch, DVM, DACT, K. M. Wendt, DVM, DACT, and D. J. Vest, DVM INTRODUCTION
Owing to the wide individual variation in estrus duration and ovulation interval in the mare, pharmacologic induction of ovulation is important for breeding situations. Since the 1970s, human chorionic gonadotropin (hCG) has been demonstrated consistently to induce ovulation and has been used routinely in broodmare practices.1-3 Numerous studies have reported that a high percentage of mares with a follicle J 35 mm in diameter will ovulate within 48 hours of hCG tratment.1,4-9 Since hCG is a large glycoprotein, repeated doses over the course of a breeding season can result in high antibody levels against hCG.10,11 Some investigators have deported decreasing ovulatory response rates with repeated hCG administration, while others have failed to demonstrate an adverse effect.2,4,11 One advantage of the use of a gonadotropin-releasing hormone (GnRH) agonist to hasten ovulation is that repeated use should not diminish efficacy.12 The GnRH agonist deslorelin (Ovuplant, Fort Dodge Animal Health, Overland Park, KS) was approved for use in mares in the United States in 1999 in the form of a controlled-release subcutaneous implant. When administered to mares with an estral follicle J 30 mm diameter, Ovuplant induces ovulation within 48 hours on over 88% of cyclic mares. 13,14 Using frequent (ie, every 2 h) examinations, McKinnon et al5 reported hCG injection resulted in a shorter interval to ovulation than deslorelin, whereas Samper et al9 reported administration of deslorelin implants resulted in a shorter interval to ovulation. One potential disadvantage to the use of deslorelin implants has been the need to remove implants at the time of ovulation in order to prevent follicular suppression and delayed return to estrus.15,16 Removal of deslorelin implants once ovulation is confirmed, while a relatively straightforward process, may be objectionable to some practitioners or mare owners.
Recent research demonstrated that deslorelin implants was effective for inducing ovulation when administered intramuscularly in a short-term biodegradable liquid.17 In 2003, a short-term-release (less than 24 hr) deslorelin (BioRelease Deslorelin injection, BET Pharm, Lexington, KY) product in a biocompatible liquid vehicle became available. This product is administered in a single dose by intramuscular injection. The goal of this study was to compare the clinical efficacy in inducing ovulation among short-term-release deslorelin injection, deslorelin implants, and hCG in cyclic mares examined once daily.
Comparative efficacy of BioRelease Deslorelin injection for
induction of ovulation in oestrus mares: a field study
SA Finan, EL Lamkin and AO McKinnon
Effect of a Single Injection of Long-acting Progesterone on the First
Ovulation in Early and Late Spring Transitional Mares
Simon A. Staemp!i DVM, DACT, DABVP a,b, Sarah Clavier MSc, Don L. Thompson PhD c,
Patrick J. Burns PhD d, Sara K. Lyle DVM, MS, DACTa,
Angus O. McKinnon BVSc, DACT, DABVP, MSb
Evaluation of Injectable Sustained Release Progestin Formulations for Suppression of Estrus and Ovulation in Mares
…William A. Storer, Donald L. Thompson, Jr., Richard M. Gilley, and Patrick J. Burns
Evaluation of BioRelease Altrenogest LA 150 For Maintenance of Pregnancy in Mares
C.M. Morrow, D.V.M and P.J. Burns, Ph.D.
Evaluation of BioRelease P4 LA 300 in the Mare
.P. J. Burns, C. Morrow & J. Abraham
Evaluation of Sustained Release Progestin Formulations in Mares
P. J. Burns D. L. Thompson, Jr, W. A. Storer, R.M. Gilley
New Pharmacological Treatments for Equine Reproductive Management
P. J. Burns, Ph.D., D. L. Thompson, Jr, Ph.D., W. A. Storer, Ph.D., R. Gilley B.S., C. Morrow, D.V.M., J. Abraham, B.S. & R. H. Douglas, Ph.D.
Use of a Compounded Proprietary Long-Acting Progesterone Formulation for Maintenance of Pregnancy in Mares
D.K. Vanderwall, J.L. Williams and G.L. Woods
Endocrine Diagnostics in the Broodmare: What you need to know about Progestins and Estrogens
R. H. DOUGLAS
Evaluation of BioRelease Altrenogest LA 150 For Maintenance of Pregnancy in Mares
C.M. Morrow, D.V.M and P.J. Burns, Ph.D.
Evaluation of BioRelease P4 LA 300 in the Mare
.P. J. Burns, C. Morrow & J. Abraham
Evaluation of Sustained Release Progestin Formulations in Mares
P. J. Burns D. L. Thompson, Jr, W. A. Storer, R.M. Gilley
Use of a Compounded Proprietary Long-Acting Progesterone Formulation for Maintenance of Pregnancy in Mares
D.K. Vanderwall, J.L. Williams and G.L. Woods
Use of a Compounded Proprietary Long-Acting Progesterone Formulation for Maintenance of Pregnancy in Mares
…D.K. Vanderwall, J.L. Williams and G.L. Woods
Intervals to ovulation after treatment with estradiol cypionate (ECP) or Biorelease Deslorelin (BRT_DES)
…P. Fleury1, M.A. Alonso1, M.A. Alvarenga 2and R. H. Douglas
CONTROL
|
10 mg ECP
|
DES 0.5 mg
|
DES 1.0 mg
|
DES 0.5 mg + ECP
|
DES 1.0 mg + ECP
|
|||||||
30-35 mm
|
> 35mm
|
30-35 mm
|
> 35mm
|
30- 35mm
|
> 35mm
|
30-35 mm
|
> 35mm
|
30-35 mm
|
> 35mm
|
30-35m m
|
> 35mm
|
|
X
|
104.4a
|
81.0b
|
123.1c
|
99.6d
|
49.0e
|
45.8e
|
44.8e
|
40.8e
|
57.6e
|
48.0e
|
57.3e
|
45.6e
|
sem
|
6.4
|
3.7
|
4.2
|
3.6
|
3.2
|
4.5
|
2.4
|
2.0
|
9.6
|
3.1
|
7.4
|
3.0
|
Endocrine Diagnostics in the Broodmare: What you need to know about Progestins and Estrogens
R. H. DOUGLAS
Estradiol cypionate aided treatment for experimentally induced ascending placentitis in mares.
Bruna R. Curcio, Igor F. Canisso, Fernanda M. Pazinato, Luciana A. Borba, Lorena S. Feijo, Vitoria Muller, Ilusca S. Finger, Ramiro E. Toribio, Carlos E.W. Nogueira